Date of Graduation

5-2018

Document Type

Thesis

Degree Name

Bachelor of Science in Biomedical Engineering

Degree Level

Undergraduate

Department

Biomedical Engineering

Advisor

Jensen, Hanna

Reader

Quinn, Kyle

Second Reader

Jensen, Morten

Abstract

Vector flow imaging (VFI) is a new ultrasound technology that provides real time, angle-independent visualization of flow velocities in the heart and great vessels. Thus far, VFI has been used for superficial applications due to the limited penetration depth of available transducer probes; however, this depth in smaller pediatric patients enables adequate aortic views. In this project, VFI was used to study pediatric aortic stenosis (PAS)—a congenital heart defect that results in the narrowing of the aorta and/or aortic valve. The decision to refer PAS patients for surgical or catheter-based intervention is initially based on Doppler ultrasound. VFI is potentially more precise, and avoids many of the pitfalls of conventional Doppler ultrasound, namely in the under- or overestimation of pressure differences in the aorta leading to less than ideal treatment timelines. Our goal was to create a method for quantitatively analyzing vectors produced by the VFI machine and to validate VFI technology by attaching an aortic arch phantom to a customized flow loop. This research will set the foundation for the creation of patient-specific aortic arch phantoms.

Keywords

vector flow imaging, VFI, pediatric aortic stenosis, aortic stenosis, aortic phantom, phantom

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