Taste thresholds for the bitter compound sucrose octaacetate (SOA) were elevated by desalivation in mice. Thresholds were determined for control and experimental animals both before and after ligation of all salivary ducts. There was a significant increase in SOA thresholds in the desalivate mice, and the pre- to post-operative differences in threshold between the control and experimental groups were significant. The altered response to SOA by desalivate mice is shown to be due to the assumption of a prandial pattern of drinking as a result of desalivation. This conclusion is based on experiments with wet mash which failed to show any differences in threshold between the same control and desalivate mice that demonstrated a significant difference when tested on fluids and dry pellets.
Lewis, Richard C.
"Taste-Masking: Function of Exaggerated Prandial Drinking in Desalivate Mice,"
Journal of the Arkansas Academy of Science: Vol. 32
, Article 20.
Available at: http://scholarworks.uark.edu/jaas/vol32/iss1/20