Document Type

Patent

Publication Date

2-17-2015

Abstract

Vaccine vectors including an antigenic polypeptide and an HMGB1 polypeptide present on the surface of the vaccine vector are provided. Compositions comprising the vaccine vectors and include a pharmaceutically acceptable carrier, suitably a carrier for oral or nasal administration are also provided . Methods of enhancing immune responses, in particular antibody immune response and suitably an IgA response, by administering the vaccine vectors or compositions disclosed herein to a subject.

Department

Poultry Science

Patent Number

US8956618; AU2011207331 (C1); CN102811734 (B); EA023058 (B1)

Application Number

US20120282291

Application Published

11-8-2012

Application Filed

1-21-2011

Assignee

The Texas A&M University System (College Station, TX); Board of Trustees of the University of Arkansas (Little Rock, AR)

Comments

Walter G. Bottje, Department of Poultry Science
Billy M. Hargis, Department of Poultry Science
Sherryll Layton, Department of Poultry Science

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