Describes a method of producing active immunity against a bacterial or protozoal disease in a subject. It comprises administering to the subject a vaccine conjugate comprising a live bacterial or protozoa and a neutralizing factor bound to the live bacterial or protozoa. The neutralizing factor is selected from the group consisting of antibodies and antibody fragments. The live bacterial or protozoa is one capable of producing disease in the subject, and the antibody or antibody fragment is one capable of neutralizing the live bacteria or protozoa.
Chemistry and Biochemistry
EP0951299 (B1); DE69730152 (T2); ES2224273 (T3)
(EMBREX, INC, ; UNIVERSITY OF ARKANSAS)
Thoma, John A.; Haddad, Eid E.; Whitfill, Craig E.; and Avakian, Alan P., "Method of producing active immunity with vaccine conjugate" (2004). Patents Granted. 137.