Method of treating viral diseases in animals

Inventors

Craig E. Whitfill
John A. Thoma, University of Arkansas, Fayetteville
Tommy L. Fredericksen
Julius K. Tyczkowski
James P. Thaxton Jr.

Document Type

Patent

Publication Date

2-16-1999

Abstract

Describes a method of producing active immunity against a viral disease in an animal subject. It comprises of administering a vaccine conjugate consisting essentially of a live virus and a neutralizing factor bound to the live virus to the subject. The neutralizing factor is selected from the group consisting of antibodies and antibody fragments. The live virus is one capable of producing disease in the subject, and the antibody or antibody fragment is one capable of neutralizing the live virus. Preferred subjects are birds, a preferred virus is Infectious Bursal Disease Virus, and a preferred route of administration to birds is by in ovo administration.

Department

Chemistry & Biochemistry

Patent Number

US5871748

Application Filed

8-21-1996

Assignee

Embrex, Inc (Research Triangle Park, NC); University of Arkansas (Fayetteville, AR)

Comments

John A. Thoma, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR

Citation

Whitfill, C. E., Thoma, J. A., Fredericksen, T. L., Tyczkowski, J. K., & Thaxton, J. P. (1999). Method of treating viral diseases in animals. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/195