Methods of selecting and using therapeutic and prophylactic probiotic cultures to reduce bacterial pathogen loads

Inventors

Daniel J. Donoghue, University of Arkansas, Fayetteville
Ann M. Donoghue

Document Type

Patent

Publication Date

8-15-2015

Abstract

Methods are provided for selecting a bacterium capable of reducing pathogenic bacterial colonization of the intestinal tract in a subject comprising selecting the bacterium capable of migrating at least 0.75 cm from the point of inoculation on motility agar after incubation for 24 hours at 37° C. It is also capable of migrating from the point of inoculation to a diameter of at least 1.5 cm based on the farthest colonies from the point of inoculation on motility agar after incubation for 24 hours at 37° C. Bacteria selected using the method and compositions comprising these bacteria are also provided.

Department

Poultry Science

Patent Number

US9107938

Application Number

US 20130323218 A1

Application Published

12-5-2013

Application Filed

9-30-2011

Assignee

Board of Trustees of the University of Arkansas (Little Rock, AR); United States of America, as Represented by the Secretary of Agriculture (Washington, DC)

Comments

Daniel J. Donoghue, Department of Poultry Science, University of Arkansas, Fayetteville, AR

Citation

Donoghue, D. J., & Donoghue, A. M. (2015). Methods of selecting and using therapeutic and prophylactic probiotic cultures to reduce bacterial pathogen loads. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/283