Document Type
Patent
Publication Date
10-15-2019
Abstract
Photoluminescent proteins resistant to protein cleavage reagents are described herein. In being resistant to cleavage reagents, such photoluminesncent proteins can reduce the number of digestion or cleavage products, thereby simplifying quantification and purification of recombinant protein compositions. In some embodiments, a photoluminescent protein described herein comprises an amino acid sequence having an absence of internal methionine residues.
Department
Biological Sciences; Chemical Engineering; Chemistry & Biochemistry
Patent Number
US10442842
Application Number
US 20170253640 A1
Application Published
9-7-2017
Application Filed
3-2-2017
Assignee
Board of Trustees of the University of Arkansas (Little Rock, AR)
Citation
Beitle, R., Mukherjee, R., Kumar, T., Sakon, J., & McNabb, D. S. (2019). Cleavage resistant photoluminescent proteins and applications thereof. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/381
Comments
Robert Beitle, Jr., Department of Chemical Engineering, University of Arkansas, Fayetteville, AR
Rudra Palash Mukherjee, Department of Chemical Engineering, University of Arkansas, Fayetteville, AR
Thallapuranam Krishnaswamy Suresh Kumar, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR
Joshua Sakon, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR
David S. McNabb, Department of Biological Sciences, University of Arkansas, Fayetteville, AR