Methods of selecting wide host range bacteriophage capable of growing in a plurality of bacteria including pathogenic and non-pathogenic bacteria and bacteriophage selected by the methods are disclosed. Also disclosed are: methods of treating a subject infected with a pathogenic bacterium using bacteriophage, of decontaminating objects using bacteriophage, and of producing vaccines. In another aspect, methods of determining bacterial viability and of improving the sensitivity of a biosensor using wide host range bacteriophages are also disclosed.
(University of Arkansas, USA)
Hargis, Billy M.; Higgins, Stacy E.; Bielke, Lisa R.; Tellez, Guillermo L.; Newberry, Lisa A.; Nava, Gerardo; Donoghue, Ann M.; and Donoghue, Daniel J., "Method for bacteriophage delivery and amplification" (2011). Patents Granted. 69.