Investigation of Neurophysiological Changes in Hypothalamic Hormone Synthesis and Brain Matter Alterations During Stages of Anorexia Nervosa Recovery

Authors

Sadie Thompson, University of Arkansas, FayettevilleFollow
Emily Rothacker, University of Arkansas, FayettevilleFollow
Joshua Rorke, University of Arkansas, FayettevilleFollow
Katie Wood, University of Arkansas, FayettevilleFollow
Megan Rosa-Caldwell, University of Arkansas, FayettevilleFollow
Kevin Murach, University of Arkansas, FayettevilleFollow
Zoe MaloneFollow
Lauren BreithauptFollow
Ursula KaiserFollow
Seward RutkoveFollow

Files

Date of Graduation

5-2025

Description

Anorexia Nervosa (AN) is a severe eating disorder that causes various physiological consequences such as endocrine disruptions and neurobiological alterations. Current data is inconclusive whether these issues resolve after weight is restored. The purpose of this study is to use PCR testing and MRI analysis to investigate alterations in hypothalamic hormone synthesis and brain matter volume during simulated AN and following weight recovery with the use of an animal model.

Publication Date

2025

Document Type

Book

Degree Name

Bachelors in Exercise Science

Degree Level

Undergraduate

Department

Health, Human Performance and Recreation

Advisor/Mentor

Rosa-Caldwell, Megan

Committee Member

Rosa-Caldwell, Megan

Second Committee Member

Murach, Kevin

Disciplines

Endocrine System | Mental Disorders | Neurosciences | Physiological Processes

Keywords

Research-Based

Citation

Thompson, S., Rothacker, E., Rorke, J., Wood, K., Rosa-Caldwell, M., Murach, K., Malone, Z., Breithaupt, L., Kaiser, U., & Rutkove, S. (2025). Investigation of Neurophysiological Changes in Hypothalamic Hormone Synthesis and Brain Matter Alterations During Stages of Anorexia Nervosa Recovery. 2025 Honors Symposium. Retrieved from https://scholarworks.uark.edu/coesym25/14