Date of Graduation

5-2025

Document Type

Thesis

Degree Name

Master of Science in Poultry Science (MS)

Degree Level

Graduate

Department

Poultry Science

Advisor/Mentor

Kong, Byung-Whi

Committee Member

Owens, Casey T.

Second Committee Member

Orlowski, Sara K.

Keywords

C15orf57; Chicken; Genetics

Abstract

Discovering the functions of functionally unknown genes has made a huge impact on biological understanding including poultry species. In this thesis, C15orf57 (or C5H15orf57, chicken chromosome 5 human ortholog H15 open reading frame 57), was studied to understand its genetic characteristics and function. Chapter one is literature reviews on annotation of genes, the gene information on C15orf57, the importance of characterizing unknown genes in the genome, and what is known now about C15orf57. The Chapter 2 is for the structural characterization of C15orf57, gene expression of C15orf57 in various organ tissues using the qPCR method and effect of overexpression of C15orf57 on AP2 complex gene expression in CEL-im cells. Overall, these findings show a clear correlation between C15orf57 and the AP2 complex.

Included in

Genetics Commons

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