Date of Graduation
5-2025
Document Type
Thesis
Degree Name
Master of Science in Poultry Science (MS)
Degree Level
Graduate
Department
Poultry Science
Advisor/Mentor
Kong, Byung-Whi
Committee Member
Owens, Casey T.
Second Committee Member
Orlowski, Sara K.
Keywords
C15orf57; Chicken; Genetics
Abstract
Discovering the functions of functionally unknown genes has made a huge impact on biological understanding including poultry species. In this thesis, C15orf57 (or C5H15orf57, chicken chromosome 5 human ortholog H15 open reading frame 57), was studied to understand its genetic characteristics and function. Chapter one is literature reviews on annotation of genes, the gene information on C15orf57, the importance of characterizing unknown genes in the genome, and what is known now about C15orf57. The Chapter 2 is for the structural characterization of C15orf57, gene expression of C15orf57 in various organ tissues using the qPCR method and effect of overexpression of C15orf57 on AP2 complex gene expression in CEL-im cells. Overall, these findings show a clear correlation between C15orf57 and the AP2 complex.
Citation
Magdich, E. A. (2025). Gene Expression and Transfection of C15orf57 in Chicken show Clear Correlation to the Function of the AP2 Complex. Graduate Theses and Dissertations Retrieved from https://scholarworks.uark.edu/etd/5684