Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. Methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. In addition, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.
Chemistry and Biochemistry
US 20170106093 A1
Board of Trustees of the University of Arkansas (Little Rock, AR); The Kitasato Institute (Tokyo, JP); Montefiore Medical Center (New York, NY)
Ponnapakkam, T., Philominathan, S. T., Sakon, J., Katikaneni, R., Koide, T., Matsushita, O., & Gensure, R. C. (2019). Delivery of therapeutic agents by a collagen binding protein. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/370