Document Type
Article
Publication Date
9-2021
Keywords
Biological Sciences; Cellular Neuroscience; Sensory Neuroscience; Computing Methodology
Abstract
The spiking variability of neural networks has important implications for how information is encoded to higher brain regions. It has been well documented by numerous labs in many cortical and motor regions that spiking variability decreases with stimulus onset, yet whether this principle holds in the OB has not been tested. In stark contrast to this common view, we demonstrate that the onset of sensory input can cause an increase in the variability of neural activity in the mammalian OB. We show this in both anesthetized and awake rodents. Furthermore, we use computational models to describe the mechanisms of this phenomenon. Our findings establish sensory evoked increases in spiking variability as a viable alternative coding strategy.
Citation
Ly, C., Barreiro, A. K., Gautam, S. H., & Shew, W. L. (2021). Odor-evoked Increases in Olfactory Bulb Mitral Cell Spiking Variability. iScience, 24 (9), 102946. https://doi.org/10.1016/j.isci.2021.102946
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
