Histologically the liver of the channel catfish, Ictalurus punctatus, was found to consist of many lobules. Though not surrounded by a connective tissue sheath as they are in some animals, the lobules were discernable because all the hepatic cells in a particular area radiated from a central vein. Portal triads were scattered throughout the liver. The lobule tissue consisted of radiating cords of cells alternating with sinusoids. Glycogen was condensed into large vacuoles within these cells. Pancreatic tissue was found in the liver, always surrounding a capillary or venule. Morphologically the pancreatic cells were exocrine. Functionally, however, they may be endocrine cells because no ducts were found leading away from them. Connective tissue in the liver was scanty.

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