Preparation of a Series of Substituted N-Phenyl-5-Bromo-6-Chloro- and 5-Bromo-6-Chloronicotinates of Potential Agricultural Interest

Authors

Frank L. Setliff, University of Arkansas at Little RockFollow
Maximillia M. Muguluma, University of Arkansas at Little Rock
Jody Z. Caldwell, University of Arkansas at Little RockFollow

Abstract

Substituted phenyl esters of 5-bromo-2-chloronicotinic acid and 5 bromo 6-chloronicotinic acid were prepared. The acids were first converted to their respective acid chlorides using thionyl chloride, and the acid chlorides were immediately transformed to the esters by treatment with the appropriately substituted phenol in sodium hydroxide solution. Aunique chloride displacement of bromide was observed on attempting to convert 5,6-dibromonicotinic acid to its acid chloride

Recommended Citation

Setliff, Frank L.; Muguluma, Maximillia M.; and Caldwell, Jody Z. (1991) "Preparation of a Series of Substituted N-Phenyl-5-Bromo-6-Chloro- and 5-Bromo-6-Chloronicotinates of Potential Agricultural Interest," Journal of the Arkansas Academy of Science: Vol. 45, Article 29.
Available at: https://scholarworks.uark.edu/jaas/vol45/iss1/29