Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated with an Influenza A infection. Methods of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD154 capable of binding CD40 are also disclosed. Methods of developing a bacterial vaccine vector are disclosed. Methods of generating scarless site-specific mutations in a bacterium are also disclosed.
Animal Science; Food Science; Poultry Science
US 20160114025 A1
Board of Trustees of the University of Arkansas (Little Rock, AR)
Bottje, Walter G.; Hargis, Billy M.; Berghman, Luc; Kwon, Young M.; Cole, Kimberly; Cox, Mandy; and Layton, Sherryll, "Compositions and methods of enhancing immune responses" (2018). Patents Granted. 337.