Date of Graduation


Document Type


Degree Name

Doctor of Philosophy in Cell & Molecular Biology (PhD)

Degree Level



Biological Sciences


Steven C. Ricke

Committee Member

Ravi D. Barabote

Second Committee Member

Bennie J. Bench

Third Committee Member

Young Min Kwon

Fourth Committee Member

Jeffrey A. Lewis


Microbiome, Next generation sequencing, Poultry, Pseudomonas, slaughter


The United States poultry industry generated 38.6 billion pounds (17,500 metric ton) of meat in 2014 which averaged to 121 pounds (55 kg) per individual of the U.S that same year. Of that meat generated by the poultry industry, an estimated 1 million cases of Salmonellosis will occur. Out of the 1 million cases approximately 40, 000 to 50,000 will be confirmed cases by the CDC. Recently, the USDA has requested changes in the inspection process and are currently allowing processors more freedom to utilize innovation to drive the increase in safer and more desirable foods. The new standards set forth by the USDA and the willingness to be more flexible with processors will create an atmosphere conducive for the development of new technologies, process design, and antimicrobial intervention strategies that are synergistic with the rate at which large scale production occurs. In this review, the production process will be explored in conjunction with the regulatory statutes that govern poultry slaughter. Additionally, the mechanism in which antimicrobials interact with bacteria and the employment of Next Generation Sequencing to gain better insight of how the intervention strategies decontaminate raw meat.