Date of Graduation
12-2022
Document Type
Thesis
Degree Name
Master of Science in Poultry Science (MS)
Degree Level
Graduate
Department
Poultry Science
Advisor/Mentor
Danielle Graham
Committee Member
Billy Hargis
Second Committee Member
Guillermo Tellez-Isaias
Third Committee Member
Kabel Robbins
Keywords
cellulitis, clostridial dermatitis, Clostridium septicum
Abstract
The objective of this thesis was to optimize the hemolytic activity of two isolates of Clostridium septicum to evaluate if hemolytic titer of C. septicum antigen at time of formalin inactivation corresponded to increased serum antibody titer to the C. septicum alpha-toxin of turkeys immunized with an experimental formalin inactivated bacterin-toxoid vaccine. Chapter 1 provides a brief overview of the thesis. Chapter 2 consists of a literature review focused on clostridial dermatitis, specifically C. septicum-associated dermatitis (cellulitis) that affects commercial turkeys. Chapter 3 outlines our attempts to optimize an experimental autogenous bacterin-toxoid vaccine as a potential strategy to mitigate clostridial dermatitis in commercial turkey flocks.
Citation
Forga, A. (2022). Optimization of Clostridium septicum Antigen Production and Evaluation of Vaccine Administration Parameters for a Candidate Bacterin-Toxoid to Prevent Dermatitis in Commercial Turkeys. Graduate Theses and Dissertations Retrieved from https://scholarworks.uark.edu/etd/4734
Included in
Animal Diseases Commons, Animal Experimentation and Research Commons, Immunology of Infectious Disease Commons, Organismal Biological Physiology Commons, Poultry or Avian Science Commons