A method of producing active immunity against a bacterial or protozoal disease in a subject comprises administering to the subject a vaccine conjugate comprising a live bacteria or protozoa and a neutralizing factor bound to the live bacteria or protozoa. The neutralizing factor is selected from the group consisting of antibodies and antibody fragments. The live bacteria or protozoa is one capable of producing disease in the subject, and the antibody or antibody fragment is one capable of neutralizing the live bacteria or protozoa.
Chemistry and Biochemistry
University of Arkansas (Fayetteville, AR)
Thoma, John A.; Haddad, Eid E.; Whitfill, Craig E.; and Avakian, Alan P., "Method of treatment" (2002). Patents Granted. 152.