Methods and compositions for the controlled release of a drug or agent from a liposome using light or radiation are disclosed. Compositions comprising liposomes having a lipid layer, wherein the liposomes contain an agent, an enzyme capable of releasing the agent from the liposome, and an enzyme activator sequestered by a molecular cage are also disclosed, in addition to methods of delivering an agent to a target in a subject.
Biological Sciences; Physics
Board of Trustees of the University of Arkansas (Little Rock, AR)
Fologea, D., Salamo, G. J., Henry, R., Borrelli, M. J., & Corry, P. M. (2014). Method of controlled drug release from a liposome carrier. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/21
Daniel Fologea, Department of Physics, University of Arkansas, Fayetteville, AR
Greg J. Salamo, Department of Physics, University of Arkansas, Fayetteville, AR
Ralph Henry, Department of Biological Sciences, University of Arkansas, Fayetteville, AR