This invention related to a biocompatible scaffold that can detect redox-active chemicals and biomolecules electrochemically. In one embodiment, the biocompatible scaffold includes a substrate, and a conductive layer of TiO2-containing nanowires or nano fibers formed on the substrate, wherein the conductive layer of TiO2-containing nanowires or nanofibers is formed with a pore structure, and wherein when the biocompatible scaffold is in contact with a biological analyte, one or more proteins of the biological analyte are immobilized on a surface of the conductive layer Of TiO2- containing nanowires or nanofibers so as to generate a measurable faradic current signal.
Chemistry and Biochemistry
UNIV ARKANSAS TECHNOLOGY DEV F. (US)
Tian, Z. Ryan, "Biocompatible scaffold for sensing proteins" (2012). Patents Granted. 299.