Vaccine, vectors and methods of using the vaccine vectors to enhance the immune response to an Apicomplexan parasite and reduce the morbidity or mortality associated with subsequent infection are provided herein. The vaccine vectors include a polynucleotide encoding a Rhomboid polypeptide and optionally include an immune-stimulatory polypeptide suitably expressed on the surface of the vaccine vector.
US 20170182136 A1
Board of Trustees of the University of Arkansas (Little Rock, AR); The Texas A&M University System (College Station, TX)
Barta, John; Berghman, Luc; Shivaramaiah, Srichaitanya; Faulkner, Olivia B.; Bielke, Lisa R.; and Hargis, Billy M., "Compositions and methods of enhancing immune responses to Eimeria or limiting Eimeria infection" (2018). Patents Granted. 332.