Disclosed herein are mechanically-strained oligonucleotide constructs comprising two oligonucleotides that when hybridized results in a bent double-stranded oligonucleotide. The constructs may be used to probe oligonucleotide interactions with an analyte to detect interactions with metal ions or compounds.
US 20200115738 A1
Board of Trustees of the University of Arkansas (Little Rock, AR)
Wang, Y. (2022). Mechanically-strained Oligonucleotide Constructs And Methods Of Using The Same. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/445