Title

NMR assignment of Cdc42(T35A), an active Switch I mutant of Cdc42

Document Type

Article

Publication Date

2007

Keywords

Cdc42(T35A), Ras GTPase, Signal transduction

Abstract

Cdc42(T35A) is an active construct of Cdc42, a Ras GTPase involved in signal transduction, containing a single-point mutation in an important effector-binding region. We determined the backbone and side chain resonance assignments of 13C,15N-labelled Cdc42(T35A) from E. coli.

Comments

Principal Investigator: Paul Adams

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