NMR assignment of Cdc42(T35A), an active Switch I mutant of Cdc42

Authors

Paul D. Adams, University of Arkansas, FayettevilleFollow
Robert E. Oswald, University of Arkansas, Fayetteville

Document Type

Article - Abstract Only

Publication Date

2007

Keywords

Cdc42(T35A), Ras GTPase, Signal transduction

Abstract

Cdc42(T35A) is an active construct of Cdc42, a Ras GTPase involved in signal transduction, containing a single-point mutation in an important effector-binding region. We determined the backbone and side chain resonance assignments of 13C,15N-labelled Cdc42(T35A) from E. coli.

Comments

Principal Investigator: Paul Adams

Citation

Adams, P. D., & Oswald, R. E. (2007). NMR assignment of Cdc42(T35A), an active Switch I mutant of Cdc42. Biomolecular NMR Assignments, 1, 225-227. https://doi.org/10.1007/s12104-007-9062-8