Glycoside Hydrolysis with Sugar-Templated Microgel Catalysts

Authors

Susanne Striegler, University of Arkansas, Fayetteville
James Barnett, University of Arkansas, Fayetteville
Natasha Dunaway, University of Arkansas, Fayetteville

Document Type

Article - Abstract Only

Publication Date

2011

Keywords

catalysis, hydrolysis, microgel, binuclear copper complex, carbohydrate

Abstract

Water-soluble, carbohydrate-templated microgels are explored as catalysts for the hydrolysis of glycosidic bonds. The reaction is more than 2 orders of magnitude accelerated for templated macromolecular catalysts over low-molecular-weight complexes. The structure of the carbohydrate used as template during material preparation directs the catalytic performance of the catalysts to differentiate epimeric substrates.

Comments

A CAREER award from the National Science Foundation (CHE-0746635) to S.S. is gratefully acknowledged; the authors are indebted to Mike Miller for TEM imaging experiments.

Citation

Striegler, S., Barnett, J., & Dunaway, N. (2011). Glycoside Hydrolysis with Sugar-Templated Microgel Catalysts. ACS Catalysis, 2 (1), 50-55. https://doi.org/10.1021/cs200512w