Glycoside Hydrolysis with Sugar-Templated Microgel Catalysts
binuclear copper complex, carbohydrate, catalysis, hydrolysis, microgel
Water-soluble, carbohydrate-templated microgels are explored as catalysts for the hydrolysis of glycosidic bonds. The reaction is more than 2 orders of magnitude accelerated for templated macromolecular catalysts over low-molecular-weight complexes. The structure of the carbohydrate used as template during material preparation directs the catalytic performance of the catalysts to differentiate epimeric substrates.
Glycoside Hydrolysis with Sugar-Templated Microgel Catalysts Susanne Striegler, James D. Barnett, and Natasha A. Dunaway ACS Catalysis 2012 2 (1), 50-55 DOI: 10.1021/cs200512w