Document Type

Patent

Publication Date

12-27-2016

Abstract

Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. Methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. In addition, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.

Department

Chemistry and Biochemistry

Patent Number

US9526765

Application Number

US 20150038423 A1

Application Published

2-5-2015

Application Filed

2-11-2013

Assignee

The Kitasato Institute (JP); Montefiore Medical Center (New York, NY); The Board of Trustees of the University of Arkansas (Little Rock, AR)

Comments

STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH This invention was made with United States government support awarded by the National Institutes of Health grant number NCRR COBRE 8P30GM103450 and INBRE GM103429. The United States may have certain rights in this invention.

Joshua Sakon, Department of Chemistry and Biochemistry

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