Document Type
Patent
Publication Date
1-5-2016
Abstract
Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated with an Influenza A infection. Methods of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD154 capable of binding CD40 are also disclosed. Methods of developing a bacterial vaccine vector are disclosed. Methods of generating scarless site-specific mutations in a bacterium are also disclosed.
Department
Animal Science; Food Science; Poultry Science
Patent Number
US9226957
Application Number
US 20140093534 A1
Application Published
4-3-2014
Application Filed
12-9-2013
Assignee
Texas A&M University System (College Station, TX); Board of Trustees of the University of Arkansas (Little Rock, AR)
Citation
Bottje, W. G., Hargis, B. M., Berghman, L., Kwon, Y. M., Cole, K., Cox, M., & Layton, S. (2016). Compositions and methods of enhancing immune responses. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/275
Comments
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH This invention was made with United States government support awarded by National Institutes of Health grant R21 AI063137. The United States may have certain rights in this invention.
Walter G. Bottje, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Billy M. Hargis, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Young M. Kwon, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Kimberly Cole, Department of Animal Science, University of Arkansas, Fayetteville, AR
Mandy Cox, Department of Food Science, University of Arkansas, Fayetteville, AR
Sherryll Layton, Department of Poultry Science, University of Arkansas, Fayetteville, AR