Document Type

Patent

Publication Date

8-20-2019

Abstract

The present invention relates to the development of stable mutants of FGF-1 and FGF-2. In particular, it relates to novel engineered FGF-1 and FGF-2 polypeptides as well as polynucleotides, DNA constructs, and vectors encoding such polypeptides. In another aspect, pharmaceutical compositions and hydrogels including the disclosed polypeptides, polynucleotides, DNA constructs, and vectors are provided. In a still further aspect, methods of treating conditions using the compositions disclosed herein are provided.

Department

Biomedical Engineering; Biological Sciences; Chemistry and Biochemistry

Patent Number

US10385113

Application Number

US 20170281790 A1

Application Published

10-5-2017

Application Filed

3-30-2017

Assignee

Board of Trustees of the University of Arkansas (Fayetteville, AR)

Comments

Thallapuranam Krishnaswamy Suresh Kumar, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR
Srinivas Jayanthi, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR
Kartik Balachandran, Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR
David S. McNabb, Department of Biological Sciences, University of Arkansas, Fayetteville, AR

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