Document Type
Patent
Publication Date
8-20-2019
Abstract
The present invention relates to the development of stable mutants of FGF-1 and FGF-2. In particular, it relates to novel engineered FGF-1 and FGF-2 polypeptides as well as polynucleotides, DNA constructs, and vectors encoding such polypeptides. In another aspect, pharmaceutical compositions and hydrogels including the disclosed polypeptides, polynucleotides, DNA constructs, and vectors are provided. In a still further aspect, methods of treating conditions using the compositions disclosed herein are provided.
Department
Biological Sciences; Biomedical Engineering; Chemistry & Biochemistry
Patent Number
US10385113
Application Number
US 20170281790 A1
Application Published
10-5-2017
Application Filed
3-30-2017
Assignee
Board of Trustees of the University of Arkansas (Fayetteville, AR)
Citation
Kumar, T., Zaharoff, D. A., Jayanthi, S., Koppolu, B., Kerr, R., Balachandran, K., & McNabb, D. S. (2019). Engineered FGF compositions and methods of use thereof. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/357
Comments
Thallapuranam Krishnaswamy Suresh Kumar, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR
Srinivas Jayanthi, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR
Kartik Balachandran, Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR
David S. McNabb, Department of Biological Sciences, University of Arkansas, Fayetteville, AR