Methods of selecting wide host range bacteriophage capable of growing in a plurality of bacteria including pathogenic and non-pathogenic bacteria and bacteriophage selected by the methods are disclosed. Also disclosed are: methods of treating a subject infected with a pathogenic bacterium using bacteriophage, of decontaminating objects using bacteriophage, and of producing vaccines. In another aspect, methods of determining bacterial viability and of improving the sensitivity of a biosensor using wide host range bacteriophages are also disclosed.
(University of Arkansas, USA)
Hargis, B. M., Higgins, S. E., Bielke, L. R., Tellez, G. L., Newberry, L. A., Nava, G., Donoghue, A. M., & Donoghue, D. J. (2011). Method for bacteriophage delivery and amplification. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/69