Document Type
Patent
Publication Date
12-18-2014
Abstract
Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB 1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a pharmaceutically acceptable carrier, suitably a carrier for oral or nasal administration. Also provided are methods of enhancing immune responses, in particular antibody immune response and suitably an IgA response, by administering the vaccine vectors or compositions disclosed herein to a subject.
Department
Poultry Science
Patent Number
AU2011207331 (B2)
Application Number
AU2011207331 (A2)
Application Published
7-28-2011
Application Filed
1-21-2011
Assignee
Texas A&M University System (College Station, TX); Board of Trustees of the University of Arkansas (Little Rock, AR)
Citation
Berghman, L., Bottje, W. G., Hargis, B. M., & Layton, S. (2014). Vaccine vectors and methods of enhancing immune responses. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/295
Comments
Walter G. Bottje, Department of Poultry Science
Billy M. Hargis, Department of Poultry Science
Sherryll Layton, Department of Poultry Science