Document Type

Patent

Publication Date

12-18-2014

Abstract

Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB 1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a pharmaceutically acceptable carrier, suitably a carrier for oral or nasal administration. Also provided are methods of enhancing immune responses, in particular antibody immune response and suitably an IgA response, by administering the vaccine vectors or compositions disclosed herein to a subject.

Department

Poultry Science

Patent Number

AU2011207331 (B2)

Application Number

AU2011207331 (A2)

Application Published

7-28-2011

Application Filed

1-21-2011

Assignee

Texas A&M University System (College Station, TX); Board of Trustees of the University of Arkansas (Little Rock, AR)

Comments

Walter G. Bottje, Department of Poultry Science

Billy M. Hargis, Department of Poultry Science

Sherryll Layton, Department of Poultry Science

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