Date of Graduation
5-2025
Document Type
Thesis
Degree Name
Bachelor of Science in Biology
Degree Level
Undergraduate
Department
Chemistry & Biochemistry
Advisor/Mentor
Thallapuranam, Suresh
Committee Member
Du, Yuchun
Second Committee Member
Forbes, Kristian
Abstract
Fibroblast Growth Factors (FGFs) are a family of cell-signaling proteins. FGF, specifically the FGF-1 subfamily, which contains FGF-1 and FGF-2, is important in several biological functions such as wound healing, cell proliferation, and angiogenesis. FGF-1 has cell proliferation properties and FGF-2 has angiogenic properties. These FGFs have great potential for wound-healing therapy medications...
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Keywords
Protein Characterization; Protein Stability; Heterodimer; Wound Healing; Fibroblast Growth Factor
Citation
Letterman, A. (2025). Structural stability of FGF1-FGF2 dimer established via salt bridges with mutation K296Q. Chemistry & Biochemistry Undergraduate Honors Theses Retrieved from https://scholarworks.uark.edu/chbcuht/55