Date of Graduation
5-2018
Document Type
Thesis
Degree Name
Master of Science in Kinesiology (MS)
Degree Level
Graduate
Department
Health, Human Performance and Recreation
Advisor/Mentor
Kavouras, Stavros A.
Committee Member
Ganio, Matthew S.
Second Committee Member
Washington, Tyrone A.
Keywords
Cellular Dehydration; Glucose Regulation; Vasopressin
Abstract
A chronically elevated vasopressin level has been associated with an impaired glucose regulation system in humans. A recent study in patients with diabetes suggested that low water intake is associated with impaired glucose regulation. The aim of this study was to examine the effect of hypertonic saline infusion on glucose regulation in healthy females. Thirty healthy, non-diabetic females performed a 2-h infusion followed by a 4-h oral glucose tolerance test (OGTT). Every subject participated in two trials separated by one month, in a counterbalanced order. Two trials were identical in the procedure, differing in the concentration of saline infusion, with one trial being 3% NaCl (HYPER), another being 0.9% NaCl (ISO). The HYPER trial led to an increase in plasma osmolality (time point 0 min, 305±0.91 vs. 287±0.61 mmol/kg, P
Citation
Yang, C. (2018). The Effect of Cellular Dehydration on Glucose Regulation in Lean and Obese Females. Graduate Theses and Dissertations Retrieved from https://scholarworks.uark.edu/etd/2760
Included in
Endocrinology, Diabetes, and Metabolism Commons, Microbial Physiology Commons, Systems and Integrative Physiology Commons