Date of Graduation

12-2018

Document Type

Thesis

Degree Name

Master of Science in Kinesiology (MS)

Degree Level

Graduate

Department

Health, Human Performance and Recreation

Advisor/Mentor

Stavros Kavouras

Committee Member

Nicholas Greene

Second Committee Member

Brendon McDermott

Keywords

Dehydration, Glucose, Hydration, Metabolism

Abstract

The purpose of this study was to measure hormonal and metabolic markers in humans to see if simulating dehydration would emulate measures that are seen in prediabetic humans. 60 volunteers were divided into equal categories by sex and body mass index of normal or overweight. Participants completed two oral glucose tolerance tests (OGTT) after being intravenously infused with a isotonic or hypertonic saline solution for 120 minutes in a counter balanced order. All trials began with a euhydrated subject with a urine specific gravity (USG)

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