Date of Graduation

12-2024

Document Type

Dissertation

Degree Name

Doctor of Philosophy in Engineering (PhD)

Degree Level

Graduate

Department

Industrial Engineering

Advisor/Mentor

Chimka, Justin R.

Committee Member

Nachtmann, Heather L.

Second Committee Member

Liu, Xiao

Third Committee Member

Hernandez, Sarah V.

Keywords

tree-based framework; interpretability; interaction effects; ensemble learning; overfitting; regression methods

Abstract

This dissertation introduces a tree-based framework to improve the interpretability and modeling of interaction effects among variables, essential in fields like biostatistics, healthcare, science and engineering. Traditional regression methods often fail to clearly capture complex interactions, while tree-based approaches, despite their interpretability, face performance limitations and overfitting concerns. Our proposed interaction-sensitive tree-based method, designed for seamless integration, combines various statistical techniques tailored to different data types, leveraging ensemble learning methods to enhance accuracy and mitigate overfitting. We present methods for regression, survival analysis, and classification, validated with case studies and benchmarked against traditional models using metrics like BIC and R-squared. The results highlight our framework’s balance between interpretability and predictive performance, offering a robust solution for analyzing complex data interactions.

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