Document Type
Response or Comment
Publication Date
12-2023
Keywords
Muscle adaptation; Transcriptomics; -omics
Abstract
In the last few years, single cell and single nucleus RNA-sequencing technologies have been leveraged in exercised adult skeletal muscle to reveal complex cell type-specific regulation of muscle plasticity. Expanding -omics technology at single cell resolution, complimented by advanced computational approaches, promise to rapidly accelerate our understanding of how exercise confers its numerous beneficial effects, paving the way for cell type-specific and targeted therapeutics to increase exercise responses during aging and in the face of chronic disease.
Citation
Murach, K. A., & Peterson, C. (2023). A Muscle Exercise Research Revolution Powered by -Omics at Single Cell and Nucleus Resolution. BMC Biology, 21, 298. https://doi.org/10.1186/s12915-023-01781-1
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.