Document Type
Patent
Publication Date
1-31-2017
Abstract
Compositions with antifungal activity and methods of using such compositions are provided herein. In particular the compositions are peptides of SEQ ID NO: 1 and variations thereof. The peptides may contain L or D amino acids and may be circularized, dimerized or otherwise modified to make the compositions resistant to proteolysis. The compositions may be used to inhibit microbial growth and in particular fungal growth.
Department
Biological Sciences; Chemistry & Biochemistry
Patent Number
US9556226
Application Number
US 20160039873 A1
Application Published
2-11-2016
Application Filed
3-14-2014
Assignee
Board of Trustees of the University of Arkansas (Little Rock, AR)
Citation
Kumar, T., McNabb, D. S., Akkam, Y. H., & Nguyen, D. T. (2017). Peptides with antifungal activity and methods of using the peptides. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/307
Comments
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH This invention was made with United States government support awarded by the National Institutes of Health grant numbers 1P30RR031154 and P30 GM 103450. The United States may have certain rights in this invention.
Thallapuranam Krishnaswamy Suresh Kumar, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR
David S. McNabb, Department of Biological Sciences, University of Arkansas, Fayetteville, AR
Yazan Hussien Akkam, Cell and Molecular Biology Program, University of Arkansas, Fayetteville, AR
Duy Tu Nguyen, Cell and Molecular Biology Program, University of Arkansas, Fayetteville, AR