Document Type
Patent
Publication Date
3-13-2018
Abstract
Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a pharmaceutically acceptable carrier, suitably a carrier for oral or nasal administration. Also provided are methods of enhancing immune responses, in particular antibody immune response and suitably an IgA response, by administering the vaccine vectors or compositions disclosed herein to a subject.
Department
Poultry Science
Patent Number
US9913893
Application Number
US 20150190500 A1
Application Published
7-9-2015
Application Filed
2-16-2015
Assignee
Board of Trustees of the University of Arkansas (Little Rock, AR)
Citation
Berghman, L., Bottje, W. G., Hargis, B. M., & Layton, S. (2018). Vaccine vectors and methods of enhancing immune responses. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/339
Comments
Walter G. Bottje, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Billy M. Hargis, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Sherryll Layton, Department of Poultry Science, University of Arkansas, Fayetteville, AR