Document Type
Patent
Publication Date
4-16-2019
Abstract
Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations can be used in vaccine formulations and the vaccine formulations can be used in methods to vaccinate animals against the source of the antigen or to enhance the immune response in a subject.
Department
Poultry Science
Patent Number
US10258688
Application Number
US 20170143823 A1
Application Published
5-25-2017
Application Filed
11-29-2016
Assignee
Board of Trustees of the University of Arkansas (Fayetteville, AR)
Citation
Hargis, B. M., Pumford, N. R., Morgan, M., Shivaramaiah, S., Tellez, G. L., & Wolfenden, A. (2019). Mucosal adjuvants and delivery systems. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/366
Comments
Billy M. Hargis, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Neil R. Pumford, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Srichaitanya Shivaramaiah, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Guillermo Tellez-Isaias, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Amanda Wolfenden, Department of Poultry Science, University of Arkansas, Fayetteville, AR