Mucosal adjuvants and delivery systems

Inventors

Billy M. Hargis, University of Arkansas, FayettevilleFollow
Neil R. Pumford, University of Arkansas, FayettevilleFollow
Marion MorganFollow
Srichaitanya Shivaramaiah, University of Arkansas, FayettevilleFollow
Guillermo L. Tellez, University of Arkansas, FayettevilleFollow
Amanda Wolfenden, University of Arkansas, FayettevilleFollow

Document Type

Patent

Publication Date

4-16-2019

Abstract

Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations can be used in vaccine formulations and the vaccine formulations can be used in methods to vaccinate animals against the source of the antigen or to enhance the immune response in a subject.

Department

Poultry Science

Patent Number

US10258688

Application Number

US 20170143823 A1

Application Published

5-25-2017

Application Filed

11-29-2016

Assignee

Board of Trustees of the University of Arkansas (Fayetteville, AR)

Comments

Billy M. Hargis, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Neil R. Pumford, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Srichaitanya Shivaramaiah, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Guillermo Tellez-Isaias, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Amanda Wolfenden, Department of Poultry Science, University of Arkansas, Fayetteville, AR

Citation

Hargis, B. M., Pumford, N. R., Morgan, M., Shivaramaiah, S., Tellez, G. L., & Wolfenden, A. (2019). Mucosal adjuvants and delivery systems. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/366