Document Type
Patent
Publication Date
7-21-2020
Abstract
Vaccine vectors capable of eliciting an immune response to enteric bacteria and methods of using the same are provided. The vaccine vectors include a polynucleotide encoding a PAL polypeptide. The PAL polypeptide may be expressed on the surface of the vaccine vector. The vaccine vector may also include a second polypeptide encoding an immunostimulatory polypeptide such as a CD154 polypeptide or an HMGB1 polypeptide.
Department
Poultry Science
Patent Number
US10716840
Application Number
US 20190351042 A1
Application Published
11-21-2019
Application Filed
8-5-2019
Assignee
Board of Trustees of the University of Arkansas (Little Rock, AR); Texas A&M University System (College Station, TX)
Citation
Bielke, L. R., Layton, S., Hargis, B. M., Pumford, N. R., Faulkner, O. B., Berghman, L., & Abi-Ghanem, D. (2020). Compositions and methods of enhancing immune responses to enteric pathogens. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/368
Comments
Lisa R. Bielke, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Sherryll Layton, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Billy M. Hargis, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Neil R. Pumford, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Olivia B. Faulkner, Department of Poultry Science, University of Arkansas, Fayetteville, AR