Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing.
US 20190284252 A1
Board of Trustees of the University of Arkansas (Little Rock, AR)
Kumar, T., Agarwal, S., Gundampati, R. K., Jayanthi, S., Wang, T., Jones, J., Kolenc, O., Lam, N. T., Niyonshuti, I. I., Balachandran, K., Quinn, K., & Chen, J. (2022). Engineered FGF1 and FGF2 compositions and methods of use thereof. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/433