Document Type

Patent

Publication Date

9-13-2022

Abstract

Disclosed herein is a class of chiral binuclear metal complexes for stereoselective hydrolysis of saccharides and glycosides, and more particular chiral binuclear transition metal complex catalysts that discriminate epimeric glycosides and .alpha.- and .beta.-glycosidic bonds of saccharides in aqueous solutions at near physiological pHs. The chiral binuclear metal complexes include a Schiff-base-type ligand derived from a chiral diamino building block, and a binuclear transition metal core, each which can be varied for selectivity. The metal core is a Lewis-acidic metal ion, such as copper, zinc, lanthanum, iron and nickel. The Schiff-base may be a reduced or non-reduced Schiff-base derived from aliphatic linear, aliphatic cyclic diamino alcohols or aromatic aldehydes. The ligand can be a penta- or heptadentate ligand derived from pyridinecarbaldehydes, benzaldehydes, linear or cyclic diamines or diamino alcohols.

Department

Chemistry & Biochemistry

Patent Number

US11439993

Application Number

US 20210101138 A1

Application Published

4-8-2021

Application Filed

12-11-2020

Assignee

Board of Trustees of the University of Arkansas (Little Rock, AR)

Comments

Susanne Striegler, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR

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