Document Type
Patent
Publication Date
3-7-2023
Abstract
Orthotospovirus virions travel through the thrips foregut and enter midgut epithelial cells through the interaction between virus glycoproteins and cellular receptors with several protein motifs thought to be involved in the interaction. Single, double and triple mutant polypeptides in the soybean vein necrosis virus (SVNV)/Neohydatothrips variabilis system are provided herein and several are shown to block viral transmission from the thrips to the soybean plants. Methods for inhibiting viral transmission using these polypeptides or constructs comprising polynucleotides encoding peptides are also provided herein.
Department
Entomology; Plant Pathology
Patent Number
US11597945
Application Number
US 20210071196 A1
Application Published
3-11-2021
Application Filed
6-26-2020
Assignee
Board of Trustees of the University of Arkansas (Little Rock, AR)
Citation
Tzanetakis, I., & Zhou, J. (2023). Peptides That Block Transmission Of Orthotospoviruses And Methods Of Using The Same. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/447
Comments
Ioannis Tzanetakis, Department of Entomology and Plant Pathology
Jing Zhou, Department of Entomology and Plant Pathology