Document Type

Patent

Publication Date

9-30-2025

Abstract

Orthotospovirus virions travel through the thrips foregut and enter midgut epithelial cells through the interaction between virus glycoproteins and cellular receptors with several protein motifs thought to be involved in the interaction. Single, double and triple mutant polypeptides in the soybean vein necrosis virus (SVNV)/Neohydatothrips variabilis system are provided herein and several are shown to block viral transmission from the thrips to the soybean plants. Methods for inhibiting viral transmission using these polypeptides or constructs comprising polynucleotides encoding peptides are also provided herein.

Department

Entomology; Plant Pathology

Patent Number

US12428648

Application Number

US20230365986

Application Published

11-16-2023

Application Filed

3-6-2023

Assignee

Board of Trustees of the University of Arkansas (Little Rock, AR)

Comments

Ioannis Tzanetakis, Department of Entomology and Plant Pathology, University of Arkansas, Fayetteville, AR
Jing Zhou, Department of Entomology and Plant Pathology, University of Arkansas, Fayetteville, AR

Download

Share

COinS