Document Type
Article
Publication Date
9-2024
Keywords
HIGH-YIELD SYNTHESIS; CRYSTAL; COMPLEXATION
Abstract
Pillar[5]arene was synthesized using acyclic acetals diethoxymethane and dimethoxymethane, and cyclic acetals 1,3-dioxolane and 1,3,5-trioxane as an alternative to paraformaldehyde. Both Lewis and Brønsted acids were effective in catalyzing the hydrolysis of acetal and initiating the Friedel–Crafts reaction in pillararene synthesis.
Citation
Machireddy, B., & He, M. (2024). Cyclic and Acyclic Acetals as Safe, Nonaqueous Formaldehyde Equivalents for the Synthesis of Pillararenes. Chemical Communications, 60 (74), 10160-10163. https://doi.org/10.1039/d4cc03306j
Creative Commons License
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