Document Type
Patent
Publication Date
12-10-2013
Abstract
Salmonella enteritidis 13A strains and compositions comprising these strains are provided. Methods of enhancing an immune response against Influenza A; of reducing morbidity associated with an Influenza A infection; of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD 154 capable of binding CD40; of developing a bacterial vaccine vector are disclosed, and of generating scarless site-specific mutations in a bacterium are disclosed.
Department
Food Science; Poultry Science; Animal Science
Patent Number
US8604178; EP2066339 (B1); DK2066339 (T3); ES2520026 (T3); KR101460551 (B1); PT2066339 (E)
Application Number
US20110027309
Application Published
2-3-2011
Application Filed
9-18-2007
Assignee
Board of Trustees of the University of Arkansas (Little Rock, AR); Texas A&M University System (College Station, TX)
Citation
Bottje, W. G., Hargis, B. M., Berghman, L., Kwon, Y. M., Cole, K., Cox, M., & Layton, S. (2013). Compositions and methods of enhancing immune responses. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/30
Comments
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH This invention was made with United States government support awarded by National Institutes of Health grant R21 AI063137. The United States may have certain rights in this invention.
Walter G. Bottje, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Billy M. Hargis, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Young M. Kwon, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Kimberly Cole, Department of Animal Science, University of Arkansas, Fayetteville, AR
Mandy Cox, Department of Food Science, University of Arkansas, Fayetteville, AR
Sherryll Layton, Department of Poultry Science, University of Arkansas, Fayetteville, AR