Document Type
Patent
Publication Date
9-2-2025
Abstract
The present invention provides collagen-binding agents that can be used to treat wounds, ischemic heart disease, and other conditions. The collagen-binding agents comprise a therapeutic agent, a protease cleavage site, and a collagen-binding domain. The present invention further provides pharmaceutical compositions and biomedical devices comprising the disclosed collagen-binding agents, as well as methods for treating a condition using the collagen-binding agents.
Department
Chemical Engineering; Chemistry & Biochemistry
Patent Number
US12403179
Application Number
US 20220257715
Application Published
8-18-2022
Application Filed
2-18-2022
Assignee
Board of Trustees of the University of Arkansas (Little Rock, AR); National University Corporation Okayama University (Okayama, JP)
Citation
Sakon, J., Beitle, R., Aljewari, H. S., Matsushita, O., & Beitle, S. (2025). Release of Growth Factors at Wound Healing Stages. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/501
Comments
Joshua Sakon, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR
Robert Beitle, Department of Chemical Engineering, University of Arkansas, Fayetteville, AR
Hazim S. Aljewari, Department of Chemical Engineering, University of Arkansas, Fayetteville, AR
Stephanie Beitle, Department of Chemical Engineering, University of Arkansas, Fayetteville, AR