Document Type
Patent
Publication Date
5-5-2026
Abstract
The present invention provides immunostimulatory nucleic acids that have an affinity to a specific target protein. The present invention also provides templates and methods for making and using the immunostimulatory nucleic acids. Further, methods for linking the immunostimulatory nucleic acids to antigens and using the resulting complexes to enhance an immune response are provided.
Department
Chemistry & Biochemistry; Poultry Science
Patent Number
US12618074
Application Number
US 20220186224
Application Published
6-16-2022
Application Filed
4-13-2020
Assignee
Board of Trustees of the University of Arkansas (Little Rock, AR); Texas A&M University System (College Station, TX)
Citation
Al-Ogaili, A. S., Jiang, T., Vuong, C. N., Liyanage, R., Lay, J. O., Kumar, T. K., Berghman, L., & Kwon, Y. M. (2026). CD40 specific DNA aptamers as vaccine adjuvants. Patents Granted. Retrieved from https://scholarworks.uark.edu/pat/513
Comments
Adil Sabr Al-Ogaili, Cell and Molecular Biology Program, University of Arkansas, Fayetteville, AR
Tieshan Jiang, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Christine Nguyen Vuong, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Rohana Liyanage, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR
Jackson Oliver Lay Jr, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR
Thallapuranam Krishnaswamy Suresh Kumar, Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR
Young M. Kwon, Department of Poultry Science, University of Arkansas, Fayetteville, AR
Billy M. Hargis, Department of Poultry Science, University of Arkansas, Fayetteville, AR