Probiotics, Prebiotics, and Phytogenic Substances for Optimizing Gut Health in Poultry

Authors

Awad A. Shehata, PerNaturam GmbHFollow
Sakine Yalçın, Ankara UniversityFollow
Juan D. Latorre, University of Arkansas, FayettevilleFollow
Shereen Basiouni, Benha UniversityFollow
Youssef A. Attia, King Abdulaziz UniversityFollow
Amr Abd El-Wahab, University of Veterinary MedicineFollow
Christian Visscher, University of Veterinary MedicineFollow
Hesham R. El-Seedi, Uppsala UniversityFollow
Claudia Huber, Technische Universität MünchenFollow
Hafez M. Hafez, Free University of BerlinFollow
Wolfgang Eisenreich, Technische Universität MünchenFollow
Guillermo Tellez-Isaias, University of Arkansas, FayettevilleFollow

Document Type

Article

Publication Date

2-2022

Keywords

gut microbiota; dysbiosis; tight junctions; synbiotics; phytogenic substances; nutraceuticals; poultry; feed additives

Abstract

The gut microbiota has been designated as a hidden metabolic 'organ' because of its enormous impact on host metabolism, physiology, nutrition, and immune function. The connection between the intestinal microbiota and their respective host animals is dynamic and, in general, mutually beneficial. This complicated interaction is seen as a determinant of health and disease; thus, intestinal dysbiosis is linked with several metabolic diseases. Therefore, tractable strategies targeting the regulation of intestinal microbiota can control several diseases that are closely related to inflammatory and metabolic disorders. As a result, animal health and performance are improved. One of these strategies is related to dietary supplementation with prebiotics, probiotics, and phytogenic substances. These supplements exert their effects indirectly through manipulation of gut microbiota quality and improvement in intestinal epithelial barrier. Several phytogenic substances, such as berberine, resveratrol, curcumin, carvacrol, thymol, isoflavones and hydrolyzed fibers, have been identified as potential supplements that may also act as welcome means to reduce the usage of antibiotics in feedstock, including poultry farming, through manipulation of the gut microbiome. In addition, these compounds may improve the integrity of tight junctions by controlling tight junction-related proteins and inflammatory signaling pathways in the host animals. In this review, we discuss the role of probiotics, prebiotics, and phytogenic substances in optimizing gut function in poultry.

Citation

Shehata, A. A., Yalçın, S., Latorre, J. D., Basiouni, S., Attia, Y. A., El-Wahab, A. A., Visscher, C., El-Seedi, H. R., Huber, C., Hafez, H. M., Eisenreich, W., & Tellez-Isaias, G. (2022). Probiotics, Prebiotics, and Phytogenic Substances for Optimizing Gut Health in Poultry. Microorganisms, 10 (2), 395. https://doi.org/10.3390/microorganisms10020395

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.